Central serous chorioretinopathy is a disease that causes fluid to build up under the retina, the back part of the inner eye that sends sight information to the brain. Jul 07, 2014 central serous chorioretinopathy cscr is a relatively common cause of visual impairment in the western world, and is characterized by the accumulation of subretinal fluid in the macula. Central serous chorioretinopathy, commonly referred to as. Symptoms of central serous chorioretinopathy can include. Idiopathic central serous chorioretinopathy icsc is an uncommon disease with the potential to cause loss of visual acuity, decreased color vision, and decreased depth perception. Corticosteroids and central serous chorioretinopathy cscr. New diagnostic tools and new treatment modalities are emerging in order to improve the functional outcomes of these patients. Central serous chorioretinopathy, commonly referred to as csc, is a condition in which fluid accumulates under the retina, causing a serous fluidfilled detachment and vision loss csc most often occurs in young and middleaged adults. Retinal physician central serous chorioretinopathy. Patient information central serous chorio retinopathy cscr.
Central serous chorioretinopathy usually affects just one eye at a time, but both eyes can be affected at the same time. Central serous retinopathy chorioretinopathy retina. Central serous chorioretinopathy typically affects males from 20 to 45 years old, however, there are case reports of csr occurring in patients of 60 years or older. Central serous chorioretinopathy csc is an eye disease that causes serous retinal. The goal of the study is to examine the shortterm effects and safety of a systemic antialdosterone medication, eplerenone, in a small group of patients with central serous chorioretinopathy cscr. Central serous chorioretinopathy cscr is a relatively common cause of visual impairment in the western world, and is characterized by the accumulation of subretinal fluid in the macula. Moran core central serous chorioretinopathy case report. It is a common ocular disease characterized by decompensation of the retinal pigment epithelium rpe, which results in neurosensory retinal detachment, serous pigment epithelium. It is more common in men and typically occurs between the ages of 25 to 50 years.
Central serous chorioretinopathy is an eye disease which primarily affects middleaged people. Dont wait to treat central serous chorioretinopathy. The cause of central serous chorioretinopathy is unknown, although the conidtion is commonly associated with stress, steroid use, or type a personalities. If this does not revert spontaneously, visual disturbances occur. The cause of this condition is unknown but stress can be a risk factor. Ulbig department of ophthalmology, ludwig maximilian university of munich, munich, germany rous retinal detachment typically affecting the posterior pole, particularly the macular region fig. Central serous chorioretinopathy cscr central serous chorioretinopathy cscr is a condition that affects the retina the light sensitive tissue that lines the back of the eye. Most cases of central serous chorioretinopathy clear up in one or two months without any treatment. Request pdf central serous chorioretinopathy central serous chorioretinopathy csc is a disease of the retina characterized by serous detachment of the neurosensory retina secondary to one. To compare the efficacy and safety of subthreshold micropulse laser sml with threshold conventional laser tcl in central serous chorioretinopathy csc.
Jul 01, 2017 central serous chorioretinopathy csc is characterized by distorted vision micropsia, metamorphopsia, reduced contrast sensitivity, color desaturation due to a serous detachment of the neurosensory retina associated with leakage at the usually impermeable tight junctions between adjacent retinal pigment epithelial rpe cells. Central serous chorioretinopathy eye center of texas. This is the back part of the inner eye that sends sight information to the brain. The patient was diagnosed with central serous chorioretinopathy cscr and informed that her visual changes were likely to improve without intervention. Central serous chorioretinopathy laser treatment for retinal stress burnout disease is treatable. Central serous choroidopathy is a disease that causes fluid to build up under the retina. Impairment of visual acuity and retinal morphology following resolved chronic central serous chorioretinopathy. Central serous chorioretinopathy cscr is considered a benign, selflimiting disease. This study aims to report 3year clinical outcomes of patients treated with eplerenone for chronic cscr. Csc most often occurs in young and middleaged adults. Central serous chorioretinopathy csc is a chorioretinal disease that causes idiopathic serous detachment of the retina, which is associated with one or more. During this time, your ophthalmologist will look at your eye to see if the liquid is going away. Pdf on mar 1, 20, benjamin nicholson and others published central serous chorioretinopathy.
It is thought to occur as a result of a focal leakage at the level of the retinal pigment epithelium rpe. The effects on the retina are usually selflimited, although some people are left with permanent vision loss due to progressive and irreversible photoreceptor damage. Central serous chorioretinopathy most commonly occurs in males in their thirties to fifties. The various terms later used to describe the disease, including the current acceptable term cscr first used by gass in 1967, have omitted the relapsing characteristic from the term.
Pdf traumatic central serous chorioretinopathy prajakta. Fluid leaks from the blood vessel layer under the retina called the choroid. Central serous chorioretinopathy cscr has been reported with both topical inhaled, intranasal, epidural, intraarticular, dermal and periocular routes and systemic corticosteroid use 1 up to 30 june 2018, the centre for adverse reactions monitoring carm had received one case report of cscr and two case reports of retinal detachment associated with corticosteroid use carm id. However, atypical presentations or chronic cases are more of a challenge. Central serous chorioretinopathy is a retinal disorder which affects the macula. All patients were asked to complete questionnaires, addressing previously described risk factors for the development of csc. Signs and symptoms include dim and blurred blind spot in the center of vision. However, as many as third of the patients have recurrent episodes or chronic disease that may cause significant functional impairment. Central serous chorioretinopathy discusses the mechanisms, pathogenesis and risk factors of cscr, findings on various imaging modalities, available treatment options, and translational research into new treatment options for cscr management. A buildup of fluid results in swelling and raised retinal tissue close to the macula and may result in retinal detachment. Csr is believed to be a noninfectious and noninflammatory disease that results in a collection of fluid below the retina and retinal pigment epithelium rpe. Care must also be taken to ensure that corticosteroid.
Central serous is associated with an elevation detachment of the macula due to leakage of fluid from the circulation behind it choroidal circulation. Central serous retinopathy texas retina associates. Information was provided to the patient regarding the limited quality data for treatment of cscr with spironolactone, rifampin, epleronone, and low dose aspirin. For unknown reasons, men develop this condition more commonly than women. Central serous chorioretinopathy genetic and rare diseases.
There is currently no standard treatment or therapy for either acute or chronic cscr, a potentially debilitating eye disease. Dec 02, 2019 central serous chorioretinopathy csc is a common retina disease and has a relative high recurrence rate, etiology, and pathogenesis of which remains largely ambiguous. Sometimes there is severe vision loss or the leakage does not go away. Jun 18, 2019 central serous chorioretinopathy cscr is a disease in which a serous detachment of the neurosensory retina occurs over an area of leakage from the choriocapillaris through the retinal pigment epithelium rpe.
Central serous chorioretinopathy diagnosis and treatment. Central serous chorioretinopathy cscr is a chorioretinal disease, characterized by serous detachment of the neurosensory retina andor retinal pigment epithelium rpe with consequent accumulation of fluid 1,2,3. Central serous chorioretinopa thy csc affects roughly 10 men and two women per 100,000 peo ple, and they are often younger, workingaged in dividuals. Introduction central serous chorioretinopathy csc cscr most popularly known as csr central serous retinopathy is a sporadic disease of unknown etiology characterized by blister like serous detachment of neurosensory retina and retinal pigment epithelium rpe in the posterior pole. Central serous chorioretinopathy cscr is a disease in which a serous detachment of the neurosensory retina occurs over an area of leakage from the choriocapillaris through the retinal pigment epithelium rpe. Central serous retinopathy is an eye condition in which fluid builds up behind the retina and affects your vision. To investigate the risk factors for persistent or recurrent central serous chorioretinopathy csc. Diagram of the eye central serous chorioretinopathy cscr, refers to a collection of fluid under the retina. Eplerenone for central serous chorioretinopathy full text. In most people, csr gets better on its own and doesnt cause longterm changes to vision. Central serous chorioretinopathy cscr is a common disorder across the world with a variable prognosis without any standard of care. Central serous chorioretinopathy csc is a disorder characterized by serous retinal detachment andor retinal pigment epithelial rpe detachment, changes most often confined to the macula, and associated with leakage of fluid through the rpe into the subretinal space. Review and update for central serous chorioretinopathy synapse.
Central serous chorioretinopathy retinal consultants. Morphologic changes in acute central serous chorioretinopathy. Consecutive treatmentnaive csc patients were included from january 2017 to october 2018. Central serous chorioretinopathy cscr sankara nethralaya. Jan 30, 2014 central serous chorioretinopathy is a disease that causes fluid to build up under the retina, the back part of the inner eye that sends sight information to the brain.
However, relapsing serous detachments of the neurosensory retina are known to. Current concepts in managing central serous chorioretinopathy. The fluid leaks from the choroid the blood vessel layer under the retina. Request pdf photodynamic therapy for central serous chorioretinopathy purposecentral serous chorioretinopathy cscr is an idiopathic disorder characterised by detachment of the neurosensory. Eplerenone for central serous chorioretinopathy full.
Apr 22, 2005 central serous chorioretinopathy typically affects males from 20 to 45 years old, however, there are case reports of csr occurring in patients of 60 years or older. Central serous chorioretinopathy karger publishers. Central serous retinopathy csr is an affliction that can cause vision loss or make objects appear much smaller than they are in actuality. Information was provided to the patient regarding the limited quality data for treatment of cscr with spironolactone, rifampin. Central serous chorioretinopathy diseases and disorders. Central serous chorioretinopathy csc is a common retina disease and has a relative high recurrence rate, etiology, and pathogenesis of which remains largely ambiguous. Central serous retinopathy csr, also known as central serous chorioretinopathy csc or cscr, is an eye disease that causes visual impairment, often temporary, usually in one eye.
Central serous chorioretinopathy cscr, also known as central serous retinopathy or csr, is a condition that usually affects younger people and is characterized by a buildup of fluid underneath the retina. Central serous retinopathy csr rnib see differently. Multimodal imaging led to the description of a wide range of cscr manifestations, and highlighted the contribution of the choroid and pigment epithelium in cscr pathogenesis. Central serous chorioretinopathy cscr wills eye hospital. Central serous chorioretinopathy raffael liegl michael w. Central serous retinopathy csr or central serous chorioretinopathy cscr affects the central area of your retina known as the macula.
The fluid leaks from the blood vessel layer under the retina. Gawecki m, jaszczukmaciejewska a, jurskajasko a, et al. Central serous chorioretinopathy csc is a disease of the retina characterized by serous detachment of the neurosensory retina secondary to one or more focal lesions of the retinal pigment epithelium rpe. Central serous chorioretinopathy central serous chorioretinopathy, commonly referred to as csc, is a condition in which fluid accumulates under the retina, causing a serous fluidfilled detachment and vision loss. Jun 07, 2017 central serous retinopathy is an eye condition in which fluid builds up behind the retina and affects your vision. Central serous chorioretinopathy csc is characterized by an idiopathic circum scribed serous retinal detachment that is usually confined to the posterior pole. Central serous retinopathy csr, also known as central serous chorioretinopathy csc or cscr, is an eye disease where fluid builds up under the retina, causing distorted vision. Csc, is a condition in which fluid accumulates under the retina, causing a serous fluidfilled. However, previous studies have been limited by small cohort size and short followup duration.
Chorioretinopathy definition central serous chorioretinopathy cscr is often a straightforward clinical diagnosis when it presents as a typical serous neurosensory retinal detachment in a middleaged male. Aug 06, 2019 gawecki m, jaszczukmaciejewska a, jurskajasko a, et al. Backgroundaims the efficacy of mineralocorticoid receptor antagonist eplerenone to treat chronic central serous chorioretinopathy cscr has been established. Central serous chorioretinopathy associated with testosterone. These visual changes may become permanent and require removal of aviators from flight status. Photodynamic therapy for central serous chorioretinopathy.
Essentially, it is an idiopathic disorder which means that the precise cause is unknown. Central serous retinopathy csr is also known as idiopathic central serous chorioretinopathy icsc because the exact cause is unknown. Central serous chorioretinopathy cscr is a macular retinal serous detachment associated with one or more leak points in the pigment epithelium 1. In fact, the location and amount of fluid determines the symptomatology in patients with cscr. The effects on the retina are usually selflimited, although some people are left with permanent vision loss due to progressive and irreversible photoreceptor damage or retinal. Eplerenone for the treatment of chronic central serous. Central serous chorioretinopathy csc is an eye disease that causes serous retinal detachment in the posterior pole of the retina. Central serous chorioretinopathy cscr is a condition that causes fluid to build up underneath the center of the retina macula. Csr can cause your vision to be blurred and distorted due to fluid collecting underneath your macula. The retina is a thin, sensitive layer of tissue in the back of the eye. Department of ophthalmology, ludwig maximilian university of munich. Recently, advancements in imaging have led to a better understanding of the pathogenesis and mechanisms of this disease. Central serous chorioretinopathy cscr is a major cause of vision threat among middleaged male individuals.
This comprehensive book is written for retina specialists and surgeons, researchers and clinical practitioners in sensory systems vision, and. Central serous choroidopathy information mount sinai. Central serous chorioretinopathy the american society of retina. The cause of central serous chorioretinopathy is unknown, although the conidtion is commonly associated. Most patients have a blurred spot in the center of vision. It involves the collection of fluid under the retina. Risk factors for persistent or recurrent central serous. In csc, the fluid leakage comes from a layer of tissue under the retina, called the choroid. There is currently no standard treatment or therapy for either. Central serous chorioretinopathy the american society of. The retina sits ontop of a layer called the choroid, which is what supplies most of the retina with oxygen and nutrients. Efficacy and safety of subthreshold micropulse laser. Central serous chorioretinopathy cscr is an idiopathic disease of the posterior pole characterized by serous detachments of the retinal pigment epithelium rpe and neurosensory retina.
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